When it comes to protecting your health, prevention matters. If you’re sexually active or at higher risk for HIV, knowing your options is key. This guide introduces PrEP—a powerful way to help prevent HIV—and explains how it might fit into your care plan.
What Is PrEP?
PrEP stands for Pre-Exposure Prophylaxis. It’s a medicine that helps HIV-negative people avoid getting HIV.

- Usually taken as a pill once a day
- Also available as an injection (every 2 months after a few starter doses)
- Reduces the risk of getting HIV by up to 99% when taken daily
How Does It Work?
PrEP is a type of anti-retroviral therapy (ART). It works by stopping HIV from taking hold in your body if you’re exposed to it.
- It’s most effective when taken every day
- Works best as part of your daily health routine
- Safe and easy to use with support from your doctor

Who Should Consider PrEP?
PrEP may be right for you if you:
- Have multiple sexual partners
- Do not always use condoms or other barrier protection
- Are in a relationship with someone who is HIV-positive
- Are a man who has sex with men
- Share needles or equipment when using drugs

If you’re sexually active and unsure of your risk, talk to your doctor. PrEP can be part of staying safe and healthy.
How Do You Start PrEP?
Getting started is simple:

- Schedule a visit with your healthcare provider.
- Take a few tests (bloodwork) to make sure you’re HIV-negative.
- Start your medication—your doctor will help you choose between the pill and injection methods.
- Follow up every 3 months to check your health and get new prescriptions.
Are There Side Effects?
Most people have little to no side effects. When they do happen, they may include:
- Upset stomach
- Headache
- Nausea or dizziness
If anything feels off, let your healthcare provider know. Regular checkups help catch any issues early.

Why PrEP Matters
PrEP is one of the best tools we have to stop the spread of HIV because it is:
- Highly effective
- Easy to use
- Recommended by the U.S. Preventive Services Task Force (just like screenings for blood pressure or cancer)

PrEP is especially important for young adults. People under age 34 are at the highest risk of getting HIV, so conversations about prevention matter.
HIV prevention starts with awareness. If you’re sexually active or think you may be at risk, PrEP could be a good option for you.